lineage switch in childhood leukemia: a case report and review of literature

نویسندگان

shiva nazari pediatric congenital hematologic disorders research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

fatemeh malek pediatric respiratory diseases research center, national research institute of tuberculosis and lung diseases (nritld), shahid beheshti university of medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

navid zavvar pediatric congenital hematologic disorders research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

چکیده

acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. the conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. it has been rarely reported in the literature. in leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. herein, we report a 7-year-old child with acute lymphoblastic leukemia which switched to acute myeloid leukemia upon relapse.

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عنوان ژورنال:
iranian journal of blood and cancer

جلد ۸، شماره ۳، صفحات ۸۶-۸۷

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